FGFR2 associated with obesity and weight at birth (Haworth et al., 2014; Tian et al., 2018; Carboni et al., 2020) and with adult obesity (Wu et al., 2014); DUSP22 related to diabetes and obesity (Rizzo et al., 2020), and ZFP57 related to nutrition/neonatal diabetes (Boonen et al., 2013). The gene discussed is DUSP22; the disease is obesity due to melanocortin 4 receptor deficiency.