In another cohort study, those with NGAL ≥45 ng/ml had a substantially shorter time to AKI than those with <45 ng/ml, but NGAL was not a risk factor for AKI during admission, and NGAL performed considerably better on day 7 than throughout hospitalization, implying that NGAL has a limited time window for predicting AKI and that higher NGAL thresholds appear to help predict the progression of AKI rather than the onset of AKI (Casas-Aparicio et al., 2022). This evidence concerns the gene LCN2 and acute kidney injury.