HAVCR1 and acute kidney injury: In a comparison of three promising urinary AKI biomarkers, KIM-1, NGAL, and IL-18, urinary KIM-1 had the maximal diagnostic performance in the initial diagnosis of AKI in children with hypovolemia, cardiogenic or aseptic shock before alterations in SCr became apparent (Assadi and Sharbaf, 2019).