Moreover, a recent study by Nardo-Marino et al. showed that oxygen gradient ektacytometry measurements correlate with key hematological parameters in children with SCD such as Hb levels, HbF, lactate dehydrogenase, and reticulocyte counts (Nardo-Marino et al., 2021). The gene discussed is GSTM1; the disease is Schnyder corneal dystrophy.