NOS3 and congestive heart failure: As shown in Figure 6A, redox-related genes KLF2 (1.11 ± 0.09 f.c. sham, 0.53 ± 0.08 f.c. CHF, 0.74 ± 0.06 f.c. CHF-CBD, F 14.88 2,21), eNOS (0.79 ± 0.07 f.c. sham, 0.06 ± 0.01 f.c. CHF, 0.50 ± 0.24 f.c. CHF-CBD, F 6.61 2,27), NRF2 (2.60 ± 0.48 f.c. sham, 1.14 ± 0.29 f.c. CHF, 0.78 ± 0.16 f.c. CHF-CBD, KWS 10.75), and NQO1 (2.40 ± 0.42 f.c. sham, 0.65 ± 0.23 f.c. CHF, 0.50 ± 0.11 f.c. CHF-CBD, KWS 15.36) were all significantly downregulated in CHF and CHF-CBD tissue vs. sham (p < 0.05).