In repo>dEGFRλ,dp110CAAX flies, glia-specific knockdown of four genes essential for glial metabolism [ALDOA (Aldolase in flies), ACAT1 (CG8112), ELOVL6 (Baldspot), and LOX (Lox)] partly rescued glioma-induced phenotypes such as shorter lifespan and bigger tumor size. Here, ACAT1 is linked to glioma.