CircFBXW7 was also found to encode the FBXW7-185aa protein to affect parental gene FBXW7 (F-box and WD repeat domain containing 7) protein level and upregulated FBXW7-185aa inhibited proliferation and cell cycle acceleration in triple-negative breast cancer cells, while downregulated FBXW7-185aa promoted malignant phenotypes in vitro and in vivo (44). This evidence concerns the gene FBXW7 and triple-negative breast carcinoma.