Being similar to T2D, LADA patients possessed higher frequencies of CD4+ Tem and CD8+ Tem cells than NGT and T1D subjects (CD4+ Tem: T2D vs. NGT, p<0.001; T2D vs. T1D, p<0.001; T2D vs.LADA, p<0.001; LADA vs. NGT, p<0.01; LADA vs. T1D, p<0.01; CD8+ Tem: T2D vs. NGT, p<0.001; T2D vs. T1D, p<0.001; T2D vs. LADA, p<0.05; LADA vs. T1D, p<0.05; Figures 2D, E). The gene discussed is CD8A; the disease is type 1 diabetes mellitus.