IGHA1 and systemic lupus erythematosus: Based on these findings, we designed a method to evaluate the N-glycosylation and O-glycosylation status of B cells, their subsets and the produced IgA1, IgA2 and IgG immunoglobulins from pSS and SLE patients in comparison to HDs using flow cytometry and ELISA-derived approaches that combine lectins.