In addition, the chronic neurological aspects of traumatic brain injury, post-stroke syndrome, long COVID-19, intractable Lyme disease, and influenza encephalopathy have close pathophysiological similarities, mainly involving positive feedback loops for TNF maintenance and activation (185), and cerebral venous sinus thrombosis (CVT) formation is also associated with infection with SARS-CoV-2 virus (139). The gene discussed is TNF; the disease is COVID-19.