Among the urinary proteins that performed best in distinguishing and correlating with renal disease activity with high sensitivity and specificity were activated leukocyte cell adhesion molecule (ALCAM), calpastatin, hemopexin, peroxiredoxin-6 (PRX6), platelet factor-4 (PF-4), properdin, tissue factor pathway inhibitor (TFPI), and vascular cell adhesion protein-1 (VCAM-1). This evidence concerns the gene PF4 and kidney disorder.