The positive rates of thyroid peroxidase antibody (TPO-Ab), celiac disease-related transglutaminase antibody (tTG-Ab), and Addison’s disease-related 21-hydroxylase antibody (21OH-Ab) in Chinese LADA patients were 16.3%, 2.1% and 1.8%, respectively (49). This evidence concerns the gene TPO and primary adrenal insufficiency.