GWAS of Caucasians have confirmed that non-HLA genes related to GADA, including the insulin gene (INS), cytotoxic T lymphocyte-associated protein 4 gene (CTLA4), SH2B adaptor protein 3 gene (SH2B3), and others are related to LADA (35). This evidence concerns the gene SH2B3 and latent autoimmune diabetes in adults.