WHO mentions sensitivity and specificity values for diagnostic methods as follows: 100% and 100% for liquid gold standard culture, 92% and 99% for Xpert Gene test, 61% and 98% for conventional sputum-smear microscopy, and 24% and 94% for chest radiography after negative sputum test or Xpert Gene test (8); our meta-analysis confirms 82% sensitivity and 82% specificity for CRP at 8 mg/L, underlining its accuracy as a screening strategy for active TB cases among HIV-positive patients. Here, CRP is linked to tuberculosis.