For example, ATAXIC scores had a significant positive correlation with the enrichment scores of TGF-β in 6 breast cancers, 9 gliomas, 10 prostate cancers, 7 RCCs, 6 sarcomas, 5 melanomas, 13 lung cancers, and 14 liver cancers (Spearman correlation, FDR < 0.05) (Figure 4 and Supplementary Figure S2A), compared to the significant negative correlation between them in 1 sarcoma and 2 lung cancers. The gene discussed is TGFB1; the disease is Familial prostate cancer.