CDCP1 is eminently located on the cytomembrane, which lies at the nexus of critical tumorigenic signaling cascades, containing the SRC-PKCδ, PI3K-AKT, WNT, and RAS-ERK axes, the oxidative pentose phosphate pathway, and fatty acid oxidation, making significantly functional contributions to tumor progression and development [21]. The gene discussed is SRC; the disease is neoplasm.