As shown in Figure 3(d), ACC (P=1.01E − 06), BLCA (P=7.20E − 07), CHOL (P=0.0447), COAD (P=0.0025), HNSC (P=0.0137), KICH (P=0.0036), KIRC (P=0.0048), acute myeloid leukemia (LAML, P=0.0237), LGG (P=4.13E − 16), LUSC (P=1.15E − 05), PAAD (P=1.71E − 08), SARC (P=5.50E − 06), SKCM (P=1.31E − 06), UCEC (P=0.0099), and uterine carcinosarcoma (UCS, P=0.0021) in CDK1 expression were positively correlated with TMB, while CDK1 expression in thymoma (THYM, P=4.71E − 11) was negatively correlated with TMB. The gene discussed is CDK1; the disease is acute myeloid leukemia.