In tube formation and transwell assays, along with the Western blot assay, we disclosed that after anlotinib treatment, tumor angiogenesis, migration, and invasion of TE-1R and KYSE-150R cells were inhibited, and protein expression of angiogenesis-related factors VEGF and bFGF was reduced (Figures 2(b)–2(e)). The gene discussed is FGF2; the disease is neoplasm.