During subsequent years, several groups have investigated the intrinsic excitability of other mouse models of AD as well as tissue from rodent brains treated with amyloid beta peptides (Brown et al., 2011; Kerrigan et al., 2014; Siskova et al., 2014; Tamagnini et al., 2015a,b; Musial et al., 2018; Yao et al., 2020, 2022; Liu et al., 2021; Russo et al., 2021; Vitale et al., 2021). Here, APP is linked to Alzheimer disease.