CRP and Cowden syndrome 1: Plasma leptin levels in CS patients were positively correlated with BMI (r = 0.572), TC (r = 0.268), TG (r = 0.313), LDL-C (r = 0.245), insulin (r = 0.595), HOMA-IR (r = 0.543) and hs-CRP levels (r = 0.250), and were negatively correlated with gender (male = 1, Female = 2) (r = −0.625), positive factor scores (r = −0.163), negative factor scores (r = −0.212), cognitive factor scores (r = −0.186) and PANSS total scores (r = −0.198), significantly.