Second, neutrophils also play a role in promoting tumor cell proliferation by secreting some proteolytic enzymes and serine proteases, stimulating tumor angiogenesis by secreting some proangiogenic factors like the vascular endothelial growth factor (VEGF), and inducing local immunosuppression through impairing T-cell responses and inducing T-cell death (34). The gene discussed is VEGFA; the disease is neoplasm.