Expression of the channel throughout the peripheral and central auditory system is well situated to impact the neurophysiological underpinnings of the tinnitus percept, as BK channel activity can regulate input into, and local activity within the AC where sound perception arises (Knaus et al., 1996; Sivaramakrishnan and Oliver, 2001; Thurm et al., 2005; Oliver et al., 2006; Sausbier et al., 2006; Pyott et al., 2007; He et al., 2014; Scott et al., 2017). Here, KCNMA1 is linked to Tinnitus.