The results showed that the pathways mainly included chemokine signal pathway, B-cell receptor signal pathway, NOD-like receptor signal pathway, NF-κB signal pathway, phosphatidylinositol signal pathway, cAMP signal pathway, cytokine–cytokine receptor interaction, rheumatoid arthritis, primary immunodeficiency disease, platelet activation, etc. (Figure 8A). Here, NFKB1 is linked to inborn error of immunity.