Again, this group confirmed the association with SCLC-N, when they evaluated neurogenic transcription factors in responders and non-responders and also found that the elevated NEUROD1 and low ASCL1, markers of SCLC-N, were associated with downregulation of antiviral IFN gene signaling (Miles et al., 2017). Here, NEUROD1 is linked to small cell lung carcinoma.