GPX4 and neurodegenerative disease: FSP1 catalyzes the regeneration of CoQ10 through NAD(P)H, and the FSP1-CoQ10-NAD(P)H pathway, together with GPX4 and GSH, inhibits phospholipid peroxidation and ferroptosis, offering broad prospects for the treatment of degenerative diseases caused by ferroptosis (Doll et al., 2019; Chen et al., 2020; Mao et al., 2020; Reichert et al., 2020; Stockwell et al., 2020; Yan et al., 2021).