An increased p53 amyloid aggregation is present in endometrium carcinoma cell lines expressing a truncated p53 isoform at the NTD (Δ40), confirming that the p53 NTD has an intramolecular downregulatory role on p53 aggregation (Melo Dos Santos et al., 2019). This evidence concerns the gene TP53 and endometrial carcinoma.