TP53 and cancer: β-Hydroxybutyrylation at Lys120, Lys319, and Lys370 reduces p53 acetylation and decreases transcription of p53-dependent genes (Liu et al., 2019); crotonylation at Ser46 seems to inhibit p53 activity, mainly increasing p53-dependent glycolytic activity and cancer cell proliferation upon DNA damage or metabolic stress (Liao et al., 2020).