To see the DNA binding consequences of cancer-associated missense mutations of RUNX1 and wild type RUNX1, we respectively explored Jurkat-cell RUNX1-ChIP-Seq (GSE17954) and LNCaP-cell RUNX1 Chip-Seq (GSM1527839) (Dasari and Tchounwou 2014), and used the homer motif of the RUNX1-ETS complex for the protein DNA model (Figure 1D). Here, RUNX1 is linked to cancer.