Correlation analyses between OCT measurements and AD biomarker results showed that the GCL thickness was positively correlated with CSF Aβ42/Aβ40 (β = 0.364; p = 0.015) and negatively associated with CSF p‐tau concentrations (β = −0.328; p = 0.030) in the AD group. This evidence concerns the gene MAPT and Alzheimer disease.