In order to gain insight into consistency of susceptibility patterns across SMA mouse models, we compared patterns of selectively vulnerable muscles across the four most commonly used SMA mouse models: the Smn-/-;SMN2, Taiwanese, SMN∆7 and Smn2B/− mouse model, supplemented by our own analysis from the Smn2B/- mouse model (Fig. 1) and SMN∆7 (Supplementary Figure 2) [14, 20, 24, 25, 27–29]. This evidence concerns the gene SMN1 and proximal spinal muscular atrophy.