KRAS and Zika virus infectious disease: When Hc-CATH was maintained in the cell culture after ZIKV infection, Hc-CATH did not reduce the intracellular ZIKV RNA (Fig. 9B), NS3 protein (Fig. 9, C and D), E protein (Fig. 9E), and extracellular ZIKV titer (Fig. 9, F and G) in Vero cells relative to PBS.