Human cathelicidin LL-37 and its derived peptide GF-17, mouse cathelicidin CRAMP, bovine cathelicidin–derived peptide BMAP-18, Bungarus fasciatus cathelicidin-derived peptide ZY13, host defense peptide Yodha from I. aurantiaca, and Z2 from the stem region of ZIKV envelope protein are virucidal to ZIKV by disrupting the integrity of the viral membrane (28, 43, 46, 51, 54), which can directly inactivate ZIKV virion and comprise the major antiviral mechanism against ZIKV infection. Here, CAMP is linked to Zika virus infectious disease.