BECN1 and benign prostatic hyperplasia: Results showed that expression of LC3 II protein in the sh-Beclin1-BPH-1 group was obviously lower compared to the BPH-1 or sh-RNA-BPH-1 group (both p < 0.001) (Fig. 4), indicating that autophagy of BPH-1 cells could be attenuated by silencing Beclin-1.