MFRP and microphthalmia: In the present study, we also described the findings in a 44-year-old male with nanophthalmos associated with high hypermetropia and angle closure glaucoma, who had two different variants in MFRP, c.523C > T, p. (Gln175*) and c.649G > A, p. (Gly217Arg), but also demonstrated similar subretinal white/creamy spots suggesting that this finding was not limited to the c.498_499InsC mutation (Supplementary Fig. 2, Supplementary Table A).