Furthermore, several genes, including PAT1 homolog 2 (PATL2), tubulin beta 8 class VIII (TUBB8), TLE family member 6 (TLE6), cell division cycle 20 (CDC20), peptidyl arginine deiminase 6 (PADI6), NLR family pyrin domain containing 2 (NLRP2), NLR family pyrin domain containing 5 (NLRP5), KH domain containing 3 like (KHDC3L), REC114 meiotic recombination protein (REC114) and meiotic double-stranded break formation protein 1 (MEI1) [4–6], have been proved to cause early embryo arrest in human and then female infertility. Here, PADI6 is linked to female infertility.