Asymptomatic elevated cTnI level is common in the patients with chronic kidney disease or ESKD.[18,19] About 8% of the dialysis patients was reported to have elevated level of cTnI, and a higher proportion can be seen while using high-sensitive troponin.[18,19] The proportion of elevated troponin level markedly vary in the literature, attributable to different antibodies against troponin epitopes by different manufacturers with various generation immune assays.[14] There are varieties of mechanisms contributing to elevated cTnI levels in dialysis patients. This evidence concerns the gene TNNI3 and chronic kidney disease.