PLK1 and hepatocellular carcinoma: The other 38 genes (HDAC9, DDX58, CYLD, MAPK8, CFLAR, MPG, RIPK1, TARDBP, SIRT2, BRAF, BCL2L11, OTULIN, ATRX, DIABLO, STUB1, SPATA2, MLKL, MAP3K7, HAT1, FADD, ITPK1, CASP8, HSP90AA1, RNF31, HSPA4, USP22, TNFRSF21, SLC39A7, TSC1, SQSTM1, TRIM11, TRAF2, DNMT1, LEF1, PLK1, MYCN, CDKN2A, and CDKN2A) were upregulated in HCC samples (Fig. 1B).