GBP5 was associated with poor prognosis in breast cancer[38] and served as a good prognostic marker in PD-L1 and PD-1 high-expressing basal-like breast tumors.[39] A bioinformatics analysis reported that high expression of GBP1–5 was coincidentally and individually correlated with a favorable prognosis of CM patients,[40] which indicates that GBP genes may be potential prognostic biomarkers. The gene discussed is CD274; the disease is breast cancer.