CD40LG and Epstein-Barr virus infection: Parallel determination of the EBV viral-capsid antigen (VCA) IgG, Epstein-Barr nuclear antigen (EBNA) IgG and EBV IgM, enabling the discrimination of different phases of the EBV infection, indicated no association of a recent EBV infection with onset of neuroinflammation in EBV-positive CALD patients (Supplementary Fig. 4d).