ABCD1 and infection: Of note, by analysis of data characterizing the transcriptional signature of the host inflammatory response to SARS-CoV-238, a significant upregulation of ABCD1 expression in peripheral blood mononuclear cells (PBMCs) of COVID-19 patients was observed (Fig. 4j), possibly hinting at a role of ABCD1 also in the antiviral host response ensuing from infection.