Given that ZNF276 expression was not significantly correlated with estrogen receptor (ER) and progesterone receptor (PR) (Table 1), and ZNF276 did not show a significant expression characteristic in any specific subtype at the tissue and cellular levels (Fig. 1F–H), we speculated that ZNF276 expression was not significantly correlated with breast cancer subtypes. Here, ESR1 is linked to breast cancer.