The forward selection revealed that only two (CX3CL1 and EN-RAGE), two (EN-RAGE and LAP TGF-beta-1), and one (VEGF-A) inflammation-related proteins were independently, positively associated with all-cause dementia, Alzheimer’s disease, and vascular dementia, respectively. Here, CX3CL1 is linked to early-onset autosomal dominant Alzheimer disease.