Notably, basal bodies are formed in both Cep290rd16/rd16 (a model of CEP290-LCA) and Cep290−/− (a model of more severe Joubert syndrome) mouse models, with rudimentary cilia observed only in the milder Cep290rd16/rd16 retina (Rachel et al., 2015). The gene discussed is CEP290; the disease is Joubert syndrome.