SOAT1 and infection: In a similar way we could exclude the contribution of melanisation and the JAK-STAT pathway to fly protection from Pa, as flies lacking melanisation (PPO1,2,3) and cytokines of the Jak-Stat pathway (Δupd2-3) survived Pa infection at the same rate as wild-type flies (Fig 3B) and carried the same pathogen load as wild type flies (S1C Fig).