Given that we are commonly using the NPHS2‐Cre lines to assess the role of proteins of interest in the context of glomerular diseases in 2‐to 4‐month‐old animals, we decided to characterize the phenotype of heterozygous NPHS2‐Cre mice at baseline and in pathological conditions in young adult mice. Here, NPHS2 is linked to glomerular disorder.