● Understanding and speaking French ● With TTR amyloid cardiomyopathy (ATTRxt or ATTRm) confirmed by the association of:  ⚬ clinical heart failure (NYHA I-III)  ⚬ with echocardiogram and/or magnetic resonance imaging suggesting/indicating cardiac amyloidosis,  ⚬ grade 2 or 3 99mTc PYP or bone scintigraphy,  ⚬ and negative biological findings (i.e., serum immunofixation, urine immunofixation, serum free light chain assay), or, if one of those criteria is not met, amyloid deposits on biopsy specimens (from cardiac and non-cardiac sites), ● Intention to treat (Tafamadis). The gene discussed is TTR; the disease is cardiac amyloidosis.