HF fed mice had higher insulin levels after just 2 weeks of HF feeding (Std: 0.6 ± 0.0, HF: 1.9 ± 0.1 ng/ml, p = 0.003) whereas the diet did not significantly impact glucose levels until week 4 (Std: 122.7 ± 3.8, HF: 153.4 ± 3.7 mg/dl, p = 0.001). The gene discussed is INS; the disease is hydrops fetalis.