TFRC and gastric cancer: Furthermore, multivariate analysis found that N stage (P = 0.003), M stage (P = 0.003), the level of CEA (P = 0.010), the level of CA125 (P = 0.029), and TFR1 expression (P = 0.047) were the independent predictive factors in the OC of GC patients (as shown in Table 3).