Growth retardation, cardiac arrhythmias, increased heart fibrosis, early disease onset, and even premature death are shared among Lamin A/C null (Lmna−/−) mice, mice carrying Lmna point mutations (LmnaN195K/N195K mice, cardiac-specific mutation Myh6-tTA:tetO-LmnaD300N mice), and cardiac-specific knockout mice (Myh6-Cre:LmnaF/F mice)[7-9]. This evidence concerns the gene LMNA and cardiac arrhythmia.