GAS5 and atherosclerosis: With regard to lncRNA-modulated EC autophagy in atherosclerosis, it is reported that GAS5 knockdown reduces cell apoptosis in human aortic ECs in response to oxLDL, decreases SQSTM1/p62 levels, and increases LC3-II/I ratio, and these effects are reversed by suppressing miR-26a expression (102).