A race-stratified subgroup analysis observed a significant increased risk of stroke in CYP2C19 no function allele carriers of Asian ancestry (RR 1.93; 95% CI: 1.55–2.39; P < 0.001) and European ancestry (RR 2.46; 95% CI: 1.06–5.72; p = 0.04); however, the association was not statistically significant among the limited sample of African ancestry (n = 97) patients (RR 1.74; 95% CI: 0.63–4.79; p = 0.28). Here, CYP2C19 is linked to Stroke.