Genome-wide analysis of long noncoding RNAs in liver cancer indicated that TMCC1-AS1 was negatively associated with overall survival and recurrence-free survival (Cui et al., 2017).At the same time, some studies also found that TMCC1-AS1 can predict the response of HCC patients to chemotherapy and immunotherapy (Deng et al., 2020). This evidence concerns the gene TMCC1 and hepatocellular carcinoma.