The role of HAVCR2 has been found in subcutaneous panniculitis-like T-cell lymphoma (SPTCL), COAD, and esophageal carcinoma (ESCA) (O'Connell et al., 2021; Cui et al., 2021; Sonigo et al., 2020). This evidence concerns the gene HAVCR2 and colon adenocarcinoma.