To investigate the association between DNA damage and HAVCR2 expression, five DNA repair genes (PMS2, MSH2, MSH6, MLH1, and EPCAM mutations) were used to assess the relationship between HAVCR2. Our results indicated different degrees of connection between HAVCR2 expression and five DNA repair genes in pan-cancer (Figure 7C). This evidence concerns the gene MLH1 and cancer.