APPBP2 and hepatocellular carcinoma: In addition, by searching The Human Protein Atlas database (Mathias et al., 2005), immunohistochemical staining for APPBP2 was positive in HCC based on the immunohistochemistry (IHC) results (Supplementary Figure S6), as well it particularly expressed in endothelial and hepatic stellate cells referring to the cell type specific analysis (Supplementary Figure S7 and Supplementary Material).