In AKI mice, the levels of Scr, BUN and the expressions of kidney injury markers (Kidney injury molecule-1, Kim-1; and Neutrophil gelatinase-associated lipocalin, Ngal) and apoptosis-related proteins, including B-cell lymphoma-2 (Bcl-2) and Bcl-2-associated x (Bax), were markedly elevated, which were significantly ameliorated by OA treatment (Figures 1D–H). The gene discussed is HAVCR1; the disease is acute kidney injury.